Tri-G-quadruplex: controlled assembly of a G-quadruplex structure from three G-rich strands.

نویسندگان

  • Jun Zhou
  • Anne Bourdoncle
  • Frédéric Rosu
  • Valérie Gabelica
  • Jean-Louis Mergny
چکیده

In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li(+) ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na(+) ions and characterized by gel electrophoresis and spectroscopy.

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عنوان ژورنال:
  • Angewandte Chemie

دوره 51 44  شماره 

صفحات  -

تاریخ انتشار 2012